Syringe FiltersandHPLC Syringe Filter Labcompare The pores of an HPLC syringe filter will typically be 0.2, 0.22, or 0.45 µm in size. Syringe filters utilize different polymer meranes depending on the intended appliion; hydrophilic materials like nylon, MCE, and PES should be used for purifying oils or alcohol, whereas hydrophobic meranes like PTFE-B or PVDF are best applied